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enzyme design
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enzyme design
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Computational Protein Design 

The focus of the lab is the coupling of theoretical, computational, and experimental techniques for the study of structural biology. In particular, we have placed a major emphasis on developing quantitative methods for protein design with the goal of developing a fully systematic design strategy that we call "protein design automation." Our design approach has been refined and captured in a software program called TRIAD and has been applied to a variety of problems ranging from antibody engineering to the creation of de novo enzymes. 

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